Section: N/A ReadChanges --- title: What is the underlying cause of Alzheimer's disease? --- is a question about the underlying pathology of Alzheimer's disease. Alzheimer's is a highly destructive disease which affects millions of people around the world, and one for which there are very few treatment options and no known cure. ## Amyloid Hypothesis One unproven hypothesis is that Alzheimer's results from the buildup of toxic clumps in the brain called amyloid beta [@TxF0EC05]. ReadChanges